Atrial fibrillation describes very rapid contractions or twitching of the heart muscle, specifically in the atria. Most of the time, atrial fibrillation in dogs occurs secondary to heart disease. In some large breed dogs, atrial fibrillation occurs as a primary heart problem. Most dogs who develop atrial fibrillation have underlying heart disease, so the signs that are observed are related to that disease and may include exercise intolerance, cough, or difficulty breathing. Treatment varies depending on whether the dog has primary or secondary atrial fibrillation. Your dog will need to be monitored on a regular basis.