Deoxyribonucleic acid (DNA) is a long molecule that contains an animal’s entire genetic code. DNA is primarily located within the nucleus of each cell. In the nucleus, enzymes transcribe the DNA bases into a substance called RNA (ribonucleic acid), which serves as a messenger, taking the DNA message out into the cytoplasm of the cell where the RNA is translated into proteins. These proteins are responsible for a number of functions in the cell and throughout the body, primarily by acting as enzymes that regulate various cell reactions. DNA tests allow us to examine an animal’s DNA in order to see whether they carry certain genetic diseases. DNA testing can also be used to determine the ancestry of an animal.

Mutations are errors made during DNA replication. Mutations can be acquired as cells divide within the body or can be inherited if the parent’s DNA contains a mutation. Genetic markers can be used to determine genetic heritage such as breed origins.

There are multiple methods of inheritance that determine which characteristics (or phenotypes) are displayed by the offspring, including autosomal dominant, autosomal recessive, and sex-linked inheritance. There are also many polygenic traits (i.e., associated with multiple genes) as well as environmental factors that make it much more complicated to predict disease or the likelihood of passing disease onto offspring.

You’ve probably heard lots of funny cat anecdotes; about how you don’t own them…they own YOU; how they feel superior to everyone, especially dogs; that they expect to be treated like royalty. If you are considering a feline acquisition, first consider this: lots of those remarks are true! This handout explains the other factors to consider in selecting the cat most likely to choose your family, too.