Amyloidosis occurs when amyloid proteins are deposited outside cells in various tissues and organs causing tissue and organ dysfunction. It is uncommon in cats, except for Abyssinians, Siamese, Burmese, Tonkinese, Devon Rex, and Oriental shorthair breeds. Signs depend on the organs involved, but kidney involvement is most common. If kidneys are involved, signs include mouth ulcers, weight loss, vomiting, and dehydration. For cats with liver involvement, signs include weakness, pale gum color, distended abdomen, rapid heart rate, rapid breathing, abdominal pain, and collapse.