Anal sac tumors grow quickly and have a moderate risk of spreading to other parts of the body. Depending on the tumor’s size, your pet could develop signs of straining to defecate or produce thin ribbon-like stool. An increased calcium level in the blood is consistent with anal sac tumors, which can cause other signs and result in kidney failure. The best and most well-described local treatment for the primary tumor is surgery. Radiation and chemotherapy may be considered if there is evidence of spread.

The adrenal medulla is responsible for producing hormones such as epinephrine, norepinephrine, and dopamine. An adrenal medulla tumor is the result of abnormal, uncontrolled growth of the cells that produce these hormones. These tumors may go undetected for a long time and clinical signs may be subtle. These signs could include weakness, excessive panting and restlessness, newly noted anxiety, and an increase in drinking and urination. The biggest concern with these tumors is their ability to continue to grow and invade local tissues, which can make surgical removal difficult or impossible.

An adrenal cortex tumor is an abnormal growth of cells in the adrenal cortex. These tumors result in overproduction of cortisol and can be malignant (cancerous) or benign. In both cases, an adrenal cortex tumor can cause Cushing’s disease in dogs. Malignant tumors can metastasize to other organs, including the kidneys, lymph nodes, and thyroid gland. The sooner a diagnosis and treatment plan can be determined, the better the outcome for your pet.