One of the more common uroliths in the dog is composed of calcium oxalate crystals. Current research indicates that acidic urine high in calcium, citrates, or oxalates predisposes a pet to developing calcium oxalate urinary crystals and stones. The most common signs that a dog has bladder stones are increased frequency of urination, painful urination, and blood in the urine. Male dogs are more commonly affected and may be at risk of a life-threatening urinary obstruction. Treatment options and prognosis are discussed.